Capecitabina

Possible side effects of capecitabine

Like all medications, the drug has its side effects. Take the medicine and call your doctor right away if the following symptoms occur: Diarrhea is a condition in which there is a recurrence of 4 to 4 bowel movements. Vomits when urinating twice a day. Nausea: I will stop eating a lot when my food intake drastically decreases. Stomatitis is pain or swelling in the mouth/neck. Skin reaction on the feet and hands if it is painful, with itching and redness in the hand or foot.

What do you need to know before you take Capecitabine?

Capecitabine is a drug used to treat colon cancer, breast cancer. It is taken in pill form or as an injection. Capecitabine medicine can cause serious side effects, so it is important to talk to your doctor before starting treatment. Some side effects of capecitabine medication include diarrhea, vomiting, abdominal pain, and loss of appetite. hand and foot syndrome can also cause anemia and bone problems.

How to take Capecitabine?

Capecitabine is a medicine used to treat colon and breast cancer. It is taken in pill form or liquid. Capecitabine is used in adults and children. For most people, it is taken 2 times a day, 3 to 5 minutes after meals. If you have diarrhoea, Capecitabine can be taken after you have finished eating.

Capecitabine is an anticancer drug. It is used to treat breast cancer and colorectal cancer. It can also be used for other types of cancer. Capecitabine works by inhibiting the enzyme that is needed for cancer cells to divide and grow. This helps stop or slow the growth of cancer cells.

Qualitative and quantitative composition

Capecitabine belongs to a group of drugs called cytotoxics that are used to treat colon cancer and breast cancer. It is available as film-coated tablets (white: 500 mg). Capecitabine 500 mg film-coated tablets.

What is Capecitabine and what is it used for?

Capecitabine is a drug used to treat breast cancer, colon cancer, and stomach cancer. It may also be used to treat or prevent recurrence of breast cancer after surgery or chemotherapy treatment. Capecitabine is a cytostatic. Cytostatics are drugs that interfere with cell growth and reproduction, therefore they are used to treat cancer.

How to store Capecitabine

Capecitabine can be stored in its original container at room temperature (59° to 86°F), protected from light. The expiration date of the medication is printed on the container. Do not use capecitabine after the expiration date which is stated on the container. Store capecitabine away from heat and light.

Pharmaceutical form

Capecitabine is available as tablets for oral administration. Each tablet contains 500 mg capecitabine. The recommended dose of capecitabine is 1000 mg/m2 per day, administered in two divided doses (morning and evening).

Medication Name

Capecitabine is a drug used to treat colon cancer. It is used in combination with other medications to treat breast, colorectal, and pancreatic cancer. Capecitabine is taken by mouth in tablet form. Capecitabine treatment usually lasts six to eight weeks.

Capecitabine (Xeloda®)

Capecitabine (Xeloda®) is an antineoplastic drug used in the treatment of breast cancer, colon cancer, and rectal cancer. It is a cytotoxic mediation that is administered orally and directly attacks cancer cells, killing them. Capecitabine is available as a pill that is taken twice a day after meals.

1. Pharmacodynamic properties

Capecitabine is a member of the fluorouracil family, which is used in the treatment of cancer. Capecitabine is converted to 5-fluorouracil in the body. 5-Fluorouracil inhibits DNA synthesis and thus stops the growth of cancer cells. Capecitabine is effective against several types of cancer, including breast cancer, colorectal cancer, and gastric cancer.

2. Dosage and method of administration

Capecitabine is used in high-dose oral administration in order to increase the anti-tumor activity of 5-fluorouracil (5-FU). The molecular mechanism responsible for the anti-tumor activity of capecitabine is governed by the intracellular conversion of the 5'-DFUR prodrug to 5-fluorouracil, which inhibits purine synthesis and subsequently causes tumor apoptosis. Capcitabine is administered orally. , in the form of tablets. The dose and duration of treatment will be determined according to the type and stage of the tumor, as well as the patient's response to treatment. Capecitabine is available in 500 mg tablets.

3. Preclinical safety data

Capecitabine is a cytotoxic drug used in the treatment of certain types of cancer including colon cancer. Capecitabine has been shown to be effective in the treatment of metastatic colorectal cancer and advanced breast cancer. Capecitabine is also being studied in the treatment of other types of cancer. Preclinical safety data indicate that capecitabine is a safe and well-tolerated drug.

4. Special warnings and precautions for use

Capecitabine Special warnings and precautions for use: • The use of capecitabine is not recommended in patients with severe renal insufficiency (serum creatinine ≥ 3 mg/dl). If serum creatinine is ≥ 2.5 mg/dl, a reduced dose of capecitabine should be taken. The use of capecitabine is not recommended in patients with severe hepatic impairment (bilirubin ≥ 3 mg/dl) or in those with active liver disease.

If you have certain medical problems, your doctor may want you to have additional tests before taking capecitabine. These may include kidney or liver function tests. • If you are taking certain other medicines (including those sold without a prescription), your doctor may want you to avoid or reduce the amount of capecitabine you take. Some of these drugs can interfere with the body's ability to break down capecitabine. • If you are pregnant or plan to become pregnant, tell your doctor right away. Capecitabine should not be taken if you are pregnant.

5. Interaction with other drugs and other forms of interaction

Capecitabine may interact with other medications and other forms of interaction. The main form of interaction is the ability of capecitabine to inhibit xanthine transforming enzyme (XO), resulting in increased plasma levels of 6-mercaptopurine and an increased risk of toxicity. Another important side effect is the risk of severe diarrhoea, which can be fatal.

6. Fertility, pregnancy and lactation

Capecitabine is used to treat breast and colorectal cancer in women who have previously received chemotherapy treatment. Capecitabine is not recommended for pregnant or lactating women. Women of childbearing potential must avoid pregnancy during treatment with capecitabine and for one month after the end of treatment.

7. Effects on ability to drive and use machines

Capecitabine does not affect the ability to drive or use machines. However, it is recommended to avoid excessive alcohol consumption during treatment with capecitabine, as it may increase the risk of side effects such as drowsiness or difficulty concentrating.

8. Adverse reactions

Capecitabine is an oral antineoplastic drug used to treat breast cancer. It is the trademark of the drug Xeloda. Capecitabine is used alone or in combination with other cancer medications.

Capecitabine can be taken with or without food. People taking this medication may experience side effects such as nausea, vomiting, diarrhea, flatulence, back or muscle pain, constipation, tiredness, malaise, fever, chills, or excessive sweating.

9. Overdose

Capecitabine overdose can cause serious symptoms. If you take a very high dose of this medicine, you may develop nausea, vomiting, diarrhea, headaches, confusion, drowsiness, and seizures. You may also have trouble breathing or feel dizzy or lightheaded. If you experience these symptoms, immediately call your doctor or seek emergency medical attention.

10. Therapeutic indications

Capecitabine is a medicine indicated for the treatment of Hodgkin's disease, multiple myeloma, lung cancer and colorectal cancer. Capecitabine is an anticancer drug that is given as a pill or tablet. This drug is used in combination with other drugs to treat cancer.

11. List of excipients

Capecitabine has as excipients carboxymethylcellulose, magnesium stearate, hypromellose, lactose, titanium dioxide and triacetin. Carboxymethylcellulose is an agent that is responsible for regulating the viscosity of the product, while magnesium stearate is used as a lubricant. Hypromellose, on the other hand, is a substance used to give the medicine texture.

Lactose and titanium dioxide are two other ingredients on the list of excipients for capecitabine, and they perform functions similar to those mentioned above - that is, they regulate the texture and consistency of the product. Finally, triacetin is an ingredient that is used to improve the absorption of the medication.

Posology

Capecitabine dosage is 500 mg/m2/day in two doses 12 hours apart during the first 14-21 days of a cycle. If you miss a dose, take it as soon as possible. If it is too close to the eardrum for the next dose, skip it and continue on your regular schedule. Do not take a double dose to make up for missed ones.

How to take capecitabine

Before taking capecitabine, it is important to tell your doctor if you have or have had any of the following conditions: epilepsy or seizures, heart disease or problems regulating heart rate, kidney disease, or if you are taking diuretics. If you are pregnant or breast-feeding, you should also tell your doctor.

-There is not enough evidence to determine if capecitabine is safe during pregnancy. Capecitabine can pass into breast milk and may harm a nursing baby. It is not recommended that pregnant or lactating women take this medication.

Storage and handling

Capecitabine should be stored in a cool, dry place, away from heat and direct light. The handling of capecitabine requires special care to avoid contamination. Gloves should be worn and the nose and mouth covered when handling the medication.

insurance information

If you are taking capecitabine for breast cancer, insurance may help cover the cost of your treatment. Some insurance companies use a special drug system, or DSME, which covers the cost of drugs that are not available on the generic market.

Others may consider capecitabine to be an experimental drug and therefore not covered. However, if you have an insurance plan through the Federal government, such as Medicare or Medicaid, then capecitabine may be covered.

Lactation

Capecitabine is a drug used to treat breast cancer. Capecitabine has been shown to pass into breast milk and may harm a developing baby. That is why it is recommended that women who are breastfeeding do not take this drug.

Pregnancy

Capecitabine is contraindicated in pregnancy because it is excreted in breast milk and may harm a nursing baby. Animal studies have shown that capecitabine causes birth defects, abortions, and fetal malformations, and similar cases have been reported in humans.

Fertility

Capecitabine is an antineoplastic and is commonly used to treat breast cancer. However, capecitabine has been found to affect fertility as well. Studies have shown that capecitabine can damage sperm DNA and reduce the number of sperm in semen.

Capecitabine has also been found to increase the risk of miscarriage. If you're considering taking capecitabine, talk to your doctor about the possible effects on your fertility.

About Capecitabine

Capecitabine is an antineoplastic drug. It is used to treat breast cancer and colorectal cancer. It has also been used to treat stomach cancer, ovarian cancer, lung cancer, and cervical cancer. Capecitabine is in a class of drugs called cytotoxics. These drugs work by interrupting the production of cellular DNA and preventing cancer cells from dividing and growing.

Possible Side Effects

Capecitabine is a very effective medicine, but like all medicines, it has some side effects. Most side effects are mild and do not require medical treatment. Possible side effects include diarrhea, headache, and nausea. If you experience these symptoms, you should see your doctor for appropriate treatment advice.

However, some people who take this medication experience a side effect called hand-foot syndrome. This syndrome causes pain, numbness and/or itching in the hands and feet. Fortunately, hand-foot syndrome is usually temporary and goes away once capecitabine is stopped.

How long do the side effects of capecitabine last?

Some of these side effects can last up to a month after treatment has ended. Other side effects, such as diarrhea, can last for several weeks. Although most side effects are mild and can be tolerated, sometimes they can be more serious. If you experience any of these symptoms, see your doctor.

How many cycles of capecitabine are there?

Capecitabine is a medicine used to treat breast cancer. The dose of capecitabine is based on the patient's body weight and condition. It is generally recommended to take capecitabine for 3-4 cycles.

There are three cycles of capecitabine: Cycle 1, Cycle 2, and Cycle 3. Each cycle lasts one week, and the total duration of treatment is six weeks.